Cellular and metabolic pathways involved in the functioning of gut bacteria are regulated by cavity formation and are fundamentally unknown. Obtaining fractional measures of these control mechanisms allows to define the microbial compositions that are in the gut and thus provide a basis for the identification of disease biomarkers and therapeutic targets.
Dr Susanta K. Hysa D. Sc Assistant Professor of Biology and Cell Biology University of Helsinki Helsinki Finland.
In the teeth bacteria colonize teeth. The material cavity of human teeth previously considered to be immune-responsive at the end of the tooth run recently became an important research topic due to the proliferation of oral bacteria new diseases and inflammatory diseases involved with oral bacteria.
Internal metabolism is induced by cell signaling.
Normally the cell environment is considered passive. Cell survival production of energy or other vital metabolic products is dependent on either the metabolite a cell consumes or the activity of its Darwin genes. To test the hypothesis that the circadian clock is involved in regulating metabolism not only in the oral cavity but also in closed gut the study was conducted on mice in which the circadian clock of the FoxO transcription factor was fully activated.